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KMID : 1004820120130020181
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Journal of Biomedical Research
2012 Volume.13 No. 2 p.181 ~ p.187
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Sarcomatoid Carcinoma Arising from Mature Cystic Teratoma
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Son Seung-Myoung
Lee Yong-Moon
Koo Ji-Hae
Choi Song-Yi
Lee Ok-Jun
Jeong Eun-Hwan
Lee Ho-Chang
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Abstract
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Malignant transformation of mature cystic teratoma (MCT) is rare. Sarcomatoid carcinoma is a neoplasm comprising malignant mesenchymal cells and a conventional carcinomatous area. Here, we report on a case of sarcomatoid carcinoma arising from an MCT in the left ovary of a 45-year-old female. A unilocular cyst consistent with MCT was observed; however, a nodule within the cyst was confirmed from the resected ovary. Microscopically, the nodule showed both squamous cell carcinoma and pleomorphic sarcomatous components admixing with each other. Lining epithelial cells at the periphery of the main tumor showed squamous metaplasia. When a sarcomatous component is observed in the ovary tumor, it is important to find a squamous cell component, either benign or malignant.
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KEYWORD
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Teratoma, Carcinosarcoma, Dermoid cyst, Squamous cell carcinoma
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